Side effects of AJOVY

HALO phase 3 clinical trials

The most common adverse reactions reported in ≥2% of patients were injection-site reactions (including injection-site pain, injection-site induration, and injection-site erythema).¹

• <1% of patients experienced constipation vs <1% for placebo²
• <1% of patients experienced hypertension vs <1% with placebo²
• ≤2% of patients discontinued due to adverse events in the AJOVY and placebo treatment arms²
• <1% of patients in both phase 3 trials developed antibodies to AJOVY¹

Long-Term Extension study—continuation of the HALO trials*

The most common adverse reactions reported by >6% of patients were injection-site reactions (including injection-site induration, pain, erythema, hemorrhage, and pruritus).³

• No new safety signals were identified²
• 6% of patients discontinued due to lack of efficacy or adverse events²
  • Discontinuation rates were comparable for both quarterly (7%) and monthly (5%) dosing²

*The primary purpose of the Long-Term Extension study was the collection of long-term safety data. Therefore, the study was not placebo-controlled.

Please read the full Important Safety Information, and the full Prescribing Information.